Dihydrolipoamide Dehydrogenase / Biotin / 3C1
Product Details
Description | DLD (Dihydrolipoyl Dehydrogenase, Mitochondrial, Dihydrolipoamide Dehydrogenase, Glycine Cleavage System L Protein, GCSL, LAD, PHE3) (Biotin) Mab 3C1 | |
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Conjugate | Biotin | |
Clone | 3C1 | |
Target Species | Human | |
Applications | ELISA, WB, IHC | |
Supplier | US Biological | |
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About Dihydrolipoamide Dehydrogenase
This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In homodimeric form, the encoded protein functions as a dehydrogenase and is found in several multi-enzyme complexes that regulate energy metabolism. However, as a monomer, this protein can function as a protease. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In homodimeric form, the encoded protein functions as a dehydrogenase and is found in several multi-enzyme complexes that regulate energy metabolism. However, as a monomer, this protein can function as a protease. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
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