DAD1 / Biotin /
Product Details
| Description | DAD1 (Dolichyl-diphosphooligosaccharide-protein Glycosyltransferase Subunit DAD1, Oligosaccharyl Transferase Subunit DAD1, Defender Against Cell Death 1, DAD-1) (Biotin) Pab | |
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| Conjugate | Biotin | |
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| Target Species | Human | |
| Applications | ELISA | |
| Supplier | US Biological | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About DAD1
DAD1, the defender against apoptotic cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared in temperature-sensitive cells following a shift to the nonpermissive temperature, suggesting that loss of the DAD1 protein triggered apoptosis. DAD1 is believed to be a tightly associated subunit of oligosaccharyltransferase both in the intact membrane and in the purified enzyme, thus reflecting the essential nature of N-linked glycosylation in eukaryotes. [provided by RefSeq, Jul 2008]
DAD1, the defender against apoptotic cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared in temperature-sensitive cells following a shift to the nonpermissive temperature, suggesting that loss of the DAD1 protein triggered apoptosis. DAD1 is believed to be a tightly associated subunit of oligosaccharyltransferase both in the intact membrane and in the purified enzyme, thus reflecting the essential nature of N-linked glycosylation in eukaryotes. [provided by RefSeq, Jul 2008]
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