RAIDD / HRP /
Product Details
| Description | CRADD (CASP2 And RIPK1 Domain Containing Adaptor With Death Domain Protein, MGC9163, RAIDD) (HRP) Pab | |
|---|---|---|
| Conjugate | HRP | |
| Clone | ||
| Target Species | Human | |
| Applications | WB, IHC | |
| Supplier | US Biological | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About RAIDD
This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with cognitive disability. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with cognitive disability. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
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