Carbonic Anhydrase XII / PE / 1D4

Product Details
Description CA12 (Carbonic Anhydrase 12, Carbonate Dehydratase XII, Carbonic Anhydrase XII, CA-XII, Tumor Antigen HOM-RCC-3.1.3) (PE) Mab 1D4
Conjugate PE
Clone 1D4
Target Species Human
Applications ELISA, WB
Supplier US Biological
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About Carbonic Anhydrase XII
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas. Three transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2014]
About PE
Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
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394 Carbonic Anhydrase XII antibodies from over 19 suppliers available with over 41 conjugates.

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