BLNK / Biotin /

Product Details
Description BLNK, NT (BLNK, BASH, SLP65, B Cell linker protein, B Cell adapter containing a SH2 domain protein, B Cell adapter containing a Src homology 2 domain protein, Cytoplasmic adapter protein, Src homology 2 domain-containing leukocyte protein of 65kD) (Biotin) Pab
Conjugate Biotin
Clone
Target Species Human
Applications ELISA, WB
Supplier US Biological
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About BLNK
This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012]
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330 BLNK antibodies from over 21 suppliers available with over 41 conjugates.

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