Osteocalcin / HRP / 2D5

Product Details
Description BGLAP (Bone gamma-carboxyglutamate (gla) Protein, BGP, OC, PMF1) (HRP) Mab 2D5
Conjugate HRP
Clone 2D5
Target Species Human
Applications ELISA, WB
Supplier US Biological
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About Osteocalcin
This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product. [provided by RefSeq, Jun 2015]
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