SERCA1 ATPase / PE / 6F8

Product Details
Description SERCA1 (ATP2A1, ATPase, Ca++ transporting, Cardiac Muscle, Fast Twitch 1, ATP2A, OTTHUMP00000162562, SR Ca(2+)-ATPase 1, Calcium pump 1, Calcium-transporting ATPase sarcoplasmic reticulum Type, Fast Twitch skeletal Muscle isoform, Endoplasmic reticulum class 1/2 Ca(2+) ATPase, Sarcoplasmic/endoplasm) (PE) Mab 6F8
Conjugate PE
Clone 6F8
Target Species Human
Applications ELISA, WB
Supplier US Biological
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About SERCA1 ATPase
This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in three transcript variants encoding different isoforms. [provided by RefSeq, Oct 2013]
About PE
Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
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214 SERCA1 ATPase antibodies from over 18 suppliers available with over 25 conjugates.

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