About Mineralocorticoid Receptor
This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

About Cy7
Cy7 is an important historical fluorophore from GE Healthcare. It has an excitation peak at 756 nm and an emission peak at 779 nm. Spectrally its similar to Alexa Fluor™ 750.