RAX / Unconjugated /

Product Details
Description Rax (Retinal and anterior neural fold homeobox), a paired-type homeobox protein, is a human homolog of Drosophila Rx protein. It is a marker of developing eye and forebrain in vertebrates, initially expressed in the region of the forebrain where optic vesicles are formed, and is involved in promoting the division of retinal progenitor cells early in development. As development progresses, expression is seen in the retina and hypothalamus. RAX is essential for eye development. Knockout of RAX in mice eliminated eye development, and RAX mutation in humans result in Anophthalmia, where one or both eyes fail to develop.
Conjugate Unconjugated
Clone
Target Species Human
Applications WB
Supplier NSJ Bioreagents
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About RAX
This gene encodes a homeobox-containing transcription factor that functions in eye development. The gene is expressed early in the eye primordia, and is required for retinal cell fate determination and also regulates stem cell proliferation. Mutations in this gene have been reported in patients with defects in ocular development, including microphthalmia, anophthalmia, and coloboma.[provided by RefSeq, Oct 2009]
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154 RAX antibodies from over 9 suppliers available with over 27 conjugates.

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