CDK1 / Unconjugated / A17.1.1
Product Details
Description | Recognizes a 34kDa protein (cdk1), identified as Cdk1/Cdc2/p34cdc2 (a catalytic subunit of Maturation Promoting Factor). Its epitope maps near the C-terminus of the protein and its core is thought to be LGTPNNEV (aa220-227 in murine cdc2). It shows no cross reaction with cdk2 p32. It supports the kinase activity. p34cdc2 plays a crucial role during cell division and is most active during mitosis. It is a serine/threonine kinase, which is activated by cyclin, by dephosphorylation of tyrosine residues. p34cdc2 is inactivated by a tyrosine kinase. This mAb reportedly inhibits the activation of p34cdc2 kinase by cyclins. | |
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Conjugate | Unconjugated | |
Clone | A17.1.1 | |
Target Species | Human, Mouse, Rat | |
Applications | IF, IHC-P, WB, Inhibition, IP | |
Supplier | NSJ Bioreagents | |
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