Catenin alpha / Unconjugated / 1G5
Product Details
| Description | Recognizes a protein of 102kDa, identified as Catenin, alpha-1. Catenins comprise a large family of Ca2+-dependent, homotypic cell-cell adhesion molecules that play important roles in development, epithelial cell polarity and tumor progression. Alpha-Catenin is a key regulator of actin dynamics in cell-cell adhesion. During cell-cell adhesion, alpha-Catenin forms a heterodimer with beta-Catenin and links the cadherins to actin associated with the cytoskeleton. Alpha-Catenin also regulates the beta-Catenin signaling in various cells. It displays the tumor suppressor activity and is found to be down regulated in some forms of breast cancer. | |
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| Conjugate | Unconjugated | |
| Clone | 1G5 | |
| Target Species | Human | |
| Applications | FC, IF, WB | |
| Supplier | NSJ Bioreagents | |
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27 Catenin alpha antibodies from over 8 suppliers available with over 2 conjugates.
