ZNF281 / Unconjugated /

Product Details

Description	Rabbit polyclonal to ZNF281. ZNF281 antibodies represent a pair of fully characterized antibodies that recognize two different regions of a target protein. The product is developed by Biorbyt to address whether the signal observed truly represents the protein of interest, an often encountered issue in antibody pairs-based assays. The use of a pair of fully characterized vPair antibodies in the same assay can validate signal specificity since vPair antibodies recognize two independent epitopes of the same protein. Different sets of vPair antibodies are developed at Biorbyt to work with specific applications, including antibody pairs arrays, Western blot, IP-Western, ChIP, IHC, and FACS. The zinc finger protein 281 (ZNF281) belongs to the krueppel C2H2-type zinc-finger protein family. ZNF281 is involved in transcriptional regulation. ZNF281 represses the transcription of a number of genes, including gastrin and ornithine decarboxylase, by binding to the G-rich box in the enhancer region of these genes. ZNF281 is phosphorylated upon DNA damage, probably by ATM or ATR. -
Conjugate	Unconjugated
Clone
Target Species	Human, Mouse
Applications	WB
Supplier	Biorbyt
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About ZNF281
Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of gene expression; negative regulation of transcription by RNA polymerase II; and positive regulation of transcription, DNA-templated. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

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