Von Willebrand Factor / CF647 /
Product Details
| Description | Rabbit polyclonal antibody to VWF, which is also known as F8VWF and VWD. VWF is frequently found in the extracellular matrix and is expressed in the Whartons jelly-derived stem cells of placenta and mesodermal cells. It is overexpressed in the monocytes and peripheral blood mononuclear cells. It extensively acts as a chaperone for coagulation factor VIII and delivering it to the site of injury for stabilizing its heterodimeric structure and protecting it from premature clearance from plasma. This protein is important in the maintenance of hemostasis and also promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. - | |
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| Conjugate | CF647 | |
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| Target Species | Human, Mouse, Rat | |
| Applications | IF, ICC | |
| Supplier | Biorbyt | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About Von Willebrand Factor
This gene encodes a glycoprotein involved in hemostasis. The encoded preproprotein is proteolytically processed following assembly into large multimeric complexes. These complexes function in the adhesion of platelets to sites of vascular injury and the transport of various proteins in the blood. Mutations in this gene result in von Willebrand disease, an inherited bleeding disorder. An unprocessed pseudogene has been found on chromosome 22. [provided by RefSeq, Oct 2015]
This gene encodes a glycoprotein involved in hemostasis. The encoded preproprotein is proteolytically processed following assembly into large multimeric complexes. These complexes function in the adhesion of platelets to sites of vascular injury and the transport of various proteins in the blood. Mutations in this gene result in von Willebrand disease, an inherited bleeding disorder. An unprocessed pseudogene has been found on chromosome 22. [provided by RefSeq, Oct 2015]
About CF647
CF®647 from Biotium is a fluorophore with an excitation peak at 642 nm and an emission peak at 662 nm. It can be useful in both fluorescence microscopy and flow cytometry. It is spectrally similar to Alexa Fluor™ 647, DyLight™ 649 and Cy5.
CF®647 from Biotium is a fluorophore with an excitation peak at 642 nm and an emission peak at 662 nm. It can be useful in both fluorescence microscopy and flow cytometry. It is spectrally similar to Alexa Fluor™ 647, DyLight™ 649 and Cy5.
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1333 Von Willebrand Factor antibodies from over 29 suppliers available with over 50 conjugates.
