Tubulin beta 3 / Biotin /
Product Details
| Description | Rabbit polyclonal antibody to Tubulin beta3 also known as TUBB3 whose expression can be detected in the peripheral nervous system but is highly expressive in most cancerous tissues. TUBB3 plays a critical role in proper axon guidance and maintenance. It is found in the microtubule cytoskeleton. Tubulin is the major constituent of microtubules. It binds two moles of GTP one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. - | |
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| Conjugate | Biotin | |
| Clone | ||
| Target Species | Human, Mouse, Rat | |
| Applications | IF, ICC | |
| Supplier | Biorbyt | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About Tubulin beta 3
This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Oct 2010]
This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Oct 2010]
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587 Tubulin beta 3 antibodies from over 28 suppliers available with over 35 conjugates.
