Siglec-5 / Unconjugated / 1A5

Product Details
Description Mouse monoclonal antibody to SIGLEC5
Conjugate Unconjugated
Clone 1A5
Target Species Human
Applications ELISA, FC, ImmunoAssay, IF, IHC-P, WB, IP
Supplier Biorbyt
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About Siglec-5
This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. [provided by RefSeq, Feb 2012]
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