RB1 / Unconjugated /

Product Details

Description	Rabbit polyclonal to RB1. 50 μl RB1 (C-term) 0185-1) &50 μl RB1 (Middle) .vPair antibodies represent a pair of fully characterized antibodies that recognize two differentregions of a target protein. The product is developed by Biorbyt to address whether the signalobserved truly represents the protein of interest, an often encountered issue in antibody-based assays.The use of a pair of fully characterized vPair antibodies in the same assay can validate signalspecificity since vPair antibodies recognize two independent epitopes of the same protein. Differentsets of vPair antibodies are developed at Biorbyt to work with specific applications, includingantibody arrays, Western blot, IP-Western, ChIP, IHC, and FACS.
Conjugate	Unconjugated
Clone
Target Species	Human
Applications	WB
Supplier	Biorbyt
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About RB1
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008]

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