Mus81 / Biotin /

Product Details
Description Rabbit polyclonal antibody against Mus81 conjugated to Biotin
Conjugate Biotin
Clone
Target Species Human
Applications ELISA, IF, IHC-P, ICC, WB
Supplier Biorbyt
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About Mus81
This gene encodes a structure-specific endonuclease which belongs to the XPF/MUS81 endonuclease family and plays a critical role in the resolution of recombination intermediates during DNA repair after inter-strand cross-links, replication fork collapse, and DNA double-strand breaks. The encoded protein associates with one of two closely related essential meiotic endonuclease proteins (EME1 or EME2) to form a complex that processes DNA secondary structures. It contains an N-terminal DEAH helicase domain, an excision repair cross complementation group 4 (ERCC4) endonuclease domain, and two tandem C-terminal helix-hairpin-helix domains. Mice with a homozygous knockout of the orthologous gene have significant meiotic defects including the failure to repair a subset of DNA double strand breaks. [provided by RefSeq, Jun 2017]
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159 Mus81 antibodies from over 13 suppliers available with over 29 conjugates.

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