LRP-6 / Biotin /

Product Details
Description Rabbit polyclonal antibody against LRP6 conjugated to Biotin -
Conjugate Biotin
Clone
Target Species Human, Mouse, Rat
Applications
Supplier Biorbyt
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About LRP-6
This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009]
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200 LRP-6 antibodies from over 16 suppliers available with over 37 conjugates.

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