KLHL3 / Unconjugated /

Product Details
Description Rabbit polyclonal antibody to KLHL3
Conjugate Unconjugated
Clone
Target Species Human, Mouse
Applications WB
Supplier Biorbyt
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About KLHL3
This gene is ubiquitously expressed and encodes a full-length protein which has an N-terminal BTB domain followed by a BACK domain and six kelch-like repeats in the C-terminus. These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex. Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D); a rare Mendelian syndrome featuring hypertension, hyperkalaemia and metabolic acidosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2012]
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156 KLHL3 antibodies from over 12 suppliers available with over 23 conjugates.

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