Dnmt1 / ATTO 390 / 11H8

Product Details
Description Mouse monoclonal antibody against DNMT1 conjugated to ATTO-390. -
Conjugate ATTO 390
Clone 11H8
Target Species Human, Mouse
Applications ICC, WB
Supplier Biorbyt
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About Dnmt1
This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
About ATTO 390
ATTO 390 from ATTO-Tec Gmbh has an excitation peak at 390 nm and an emission peak at 448 nm.
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