DDX17 / Unconjugated /
Product Details
| Description | Rabbit polyclonal to DDX17. Probable ATP-dependent RNA helicase DDX17 belongs to the DEAD box helicase family and the DDX5/DBP2 subfamily. DDX17 is an RNA-dependent ATPase activity. DDX17 is involved in transcriptional regulation and is a transcriptional coactivator for estrogen receptor ESR1. DDX17 increases ESR1 AF-1 domain-mediated transactivation. Additionally, DDX17 synergizes with DDX5 and SRA1 RNA to activate MYOD1 transcriptional activity and is probably involved in skeletal muscle differentiation. Furthermore, DDX17 is required for zinc-finger antiviral protein ZC3HAV1-mediated mRNA degradation. | |
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| Conjugate | Unconjugated | |
| Clone | ||
| Target Species | Human | |
| Applications | WB | |
| Supplier | Biorbyt | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About DDX17
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and splicesosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an ATPase activated by a variety of RNA species, but not by dsDNA. This protein, and that encoded by DDX5 gene, are more closely related to each other than to any other member of the DEAD box family. This gene can encode multiple isoforms due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) start codon. [provided by RefSeq, Apr 2011]
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and splicesosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an ATPase activated by a variety of RNA species, but not by dsDNA. This protein, and that encoded by DDX5 gene, are more closely related to each other than to any other member of the DEAD box family. This gene can encode multiple isoforms due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) start codon. [provided by RefSeq, Apr 2011]
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175 DDX17 antibodies from over 17 suppliers available with over 34 conjugates.
