Cathepsin L / Unconjugated /

Product Details
Description Rabbit polyclonal antibody to CTSL
Conjugate Unconjugated
Clone
Target Species Human, Mouse, Rat
Applications IF, WB
Supplier Biorbyt
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About Cathepsin L
The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Additionally, this protein cleaves the S1 subunit of the SARS-CoV-2 spike protein, which is necessary for entry of the virus into the cell. [provided by RefSeq, Aug 2020]
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402 Cathepsin L antibodies from over 17 suppliers available with over 41 conjugates.

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