Endostatin / Biotin /

Product Details
Description Rabbit polyclonal antibody against COL18A1 conjugated to Biotin
Conjugate Biotin
Clone
Target Species Human
Applications ELISA
Supplier Biorbyt
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About Endostatin
This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. A long isoform of the protein has an N-terminal domain that is homologous to the extracellular part of frizzled receptors. Proteolytic processing at several endogenous cleavage sites in the C-terminal domain results in production of endostatin, a potent antiangiogenic protein that is able to inhibit angiogenesis and tumor growth. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
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414 Endostatin antibodies from over 19 suppliers available with over 41 conjugates.

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