CD20 / CF647 /

Product Details
Description CD20 antigen is a type of tumor marker. Also called CD20. There's a protein found on B cells (a type of white blood cell). It may be found in higher than normal amounts in patients with certain types of B-cell lymphomas and leukemias. Measuring the amount of CD20 antigen on blood cells may help to diagnose cancer or plan cancer treatment.The protein has no known natural ligand[8] and its function is to enable optimal B-cell immune response, specifically against T-independent antigens.It is suspected that it acts as a calcium channel in the cell membrane.It has been shown that CD20 also plays a role in the microenvironmental interactions of B cells. -
Conjugate CF647
Clone
Target Species Human, Mouse, Rat
Applications IF, ICC
Supplier Biorbyt
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About CD20
This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. [provided by RefSeq, Jul 2008]
About CF647
CF®647 from Biotium is a fluorophore with an excitation peak at 642 nm and an emission peak at 662 nm. It can be useful in both fluorescence microscopy and flow cytometry. It is spectrally similar to Alexa Fluor™ 647, DyLight™ 649 and Cy5.
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