CD114 / CF594 /

Product Details
Description CD114 is also called as CSF3R (Colony Stimulating Factor 3 Receptor) it is a Protein Coding gene. Diseases associated with CSF3R include Neutrophilia, Hereditary and Neutropenia, Severe Congenital 7, Autosomal Recessive. Among its related pathways are Innate Immune System and Pathways in cancer. GO annotations related to this gene include receptor activity and cytokine receptor activity. An important paralog of this gene is IL6ST.Receptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation. Plays a crucial role in the proliferation, differientation and survival of cells along the neutrophilic lineage. In addition it may function in some adhesion or recognition events at the cell surface. -
Conjugate CF594
Clone
Target Species Human, Mouse, Rat
Applications IF, ICC
Supplier Biorbyt
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About CD114
The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia. [provided by RefSeq, Aug 2010]
About CF594
CF®594 from Biotium is a fluorophore with an excitation peak at 593 nm and an emission peak at 614 nm. It can be useful in both fluorescence microscopy and flow cytometry. It is spectrally similar to Alexa Fluor™ 594, DyLight™ 594 and Texas Red. However, in flow cytometry, PE-CF®594 and PE-Dazzle 594 are superior alternatives. In microscopy, CF®594 has been validated in STED and 2-Photon microscopy.
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442 CD114 antibodies from over 26 suppliers available with over 64 conjugates.

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