CD114 / CF488A /

Product Details
Description CD114 is also called as CSF3R (Colony Stimulating Factor 3 Receptor) it is a Protein Coding gene. Diseases associated with CSF3R include Neutrophilia, Hereditary and Neutropenia, Severe Congenital 7, Autosomal Recessive. Among its related pathways are Innate Immune System and Pathways in cancer. GO annotations related to this gene include receptor activity and cytokine receptor activity. An important paralog of this gene is IL6ST.Receptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation. Plays a crucial role in the proliferation, differientation and survival of cells along the neutrophilic lineage. In addition it may function in some adhesion or recognition events at the cell surface. -
Conjugate CF488A
Clone
Target Species Human, Mouse, Rat
Applications IF, ICC
Supplier Biorbyt
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About CD114
The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia. [provided by RefSeq, Aug 2010]
About CF488A
CF®488A from Biotium is a fluorophore with an excitation peak at 490 nm and an emission peak at 515 nm. It is spectrally similar to Fluorescein, Alexa Fluor™ 488 and DyLight™ 488. It can be use in fluorescence microscopy and flow cytometry. In microscopy, CF®488A has been specifically validated for STORM, STED, Structured Illumination (SIM), 2-Photon microscopy and TIRF.
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442 CD114 antibodies from over 26 suppliers available with over 64 conjugates.

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