CD6 / Unconjugated /

Product Details
Description Rabbit polyclonal to CD6.CD6 is a monomeric 105-or 130-kD membrane glycoprotein that is involved in T-cell activation. CD6is also involved in cell adhesion and binds to CD166. The size difference between the two CD6 formsis due to differences in phosphorylation.
Conjugate Unconjugated
Clone
Target Species Human
Applications WB
Supplier Biorbyt
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About CD6
This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
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