Cav1.3 / Unconjugated / S48A-9

Product Details
Description Mouse monoclonal to CaV1.3. Detects ~250kDa. No cross-reactivity against Cav1.2. -
Conjugate Unconjugated
Clone S48A-9
Target Species Human, Mouse, Rat
Applications ICC, WB, IP, IHC, Microarray
Supplier Biorbyt
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About Cav1.3
Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, namely alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1D subunit. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
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