FHIT / Biotin /
Product Details
| Description | Rabbit polyclonal antibody against Bis(5'-adenosyl)-triphosphatase conjugated to Biotin | |
|---|---|---|
| Conjugate | Biotin | |
| Clone | ||
| Target Species | Human | |
| Applications | ||
| Supplier | Biorbyt | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About FHIT
The protein encoded by this gene is a P1-P3-bis(5'-adenosyl) triphosphate hydrolase involved in purine metabolism. This gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. The encoded protein is also a tumor suppressor, as loss of its activity results in replication stress and DNA damage. [provided by RefSeq, Aug 2017]
The protein encoded by this gene is a P1-P3-bis(5'-adenosyl) triphosphate hydrolase involved in purine metabolism. This gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. The encoded protein is also a tumor suppressor, as loss of its activity results in replication stress and DNA damage. [provided by RefSeq, Aug 2017]
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396 FHIT antibodies from over 19 suppliers available with over 40 conjugates.
