CD4 / Alexa Fluor 660 / RM4-5
Product Details
Description | CD4 Monoclonal Antibody (RM4-5), Alexa Fluor™ 660, eBioscience™ | |
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Conjugate | Alexa Fluor 660 | |
Clone | RM4-5 | |
Target Species | Mouse | |
Applications | FC | |
Supplier | Thermo Fisher Scientific | |
Catalog # | Sign in to view product details, citations, and spectra | |
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About CD4
This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, May 2020]
This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, May 2020]
About Alexa Fluor 660
Alexa Fluor™ 660 (AF660,Alexa 660) has an excitation peak at 663nm and an emission peak at 690nm. It can be used with the following analysis platforms: Flow Cytometry, Spectral Flow Cytometry.
Alexa Fluor™ 660 (AF660,Alexa 660) has an excitation peak at 663nm and an emission peak at 690nm. It can be used with the following analysis platforms: Flow Cytometry, Spectral Flow Cytometry.
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