Bcl-6 / Biotin / SPM602

Product Details
Description Bcl-6 Antibody (SPM602) [Biotin]
Conjugate Biotin
Clone SPM602
Target Species Human, Mouse
Applications FC, ICC, IF, IHC
Supplier Novus Biologicals
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About Bcl-6
The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015]
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