Sirtuin 2 / DyLight 350 / PCRP-SIRT2-1A8

Product Details
Description Sirtuin 2/SIRT2 Antibody (PCRP-SIRT2-1A8) [DyLight 350]
Conjugate DyLight 350
Clone PCRP-SIRT2-1A8
Target Species Human
Applications FC, ICC, IF, WB
Supplier Novus Biologicals
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About Sirtuin 2
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene. [provided by RefSeq, Jul 2010]
About DyLight 350
DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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