CD49a / Unconjugated / REA1106

Product Details

Description	Clone REA1106 recognizes the cell adhesion molecule human CD49a, which is a 200 kDa heterodimeric integrin receptor. CD49a, also known as integrin alpha1, interacts with integrin beta1 (CD29) to form the VLA-1 complex which functions as a receptor for collagen and laminin-1. Integrin alpha1 plays a role in cell-cell adhesion and T cell proliferation and is expressed by activated T cells, NK cells, neuronal cells, fibroblasts, and mesenchymal cells. \| Additional information: Clone REA1106 displays negligible binding to Fc receptors.
Conjugate	Unconjugated
Clone	REA1106
Target Species	Human
Applications	Mass Cytometry
Supplier	Miltenyi Biotec
	Catalog #	Sign in to view product details, citations, and spectra
	Size
	Price
	Antigen
	Host
	Isotype

About CD49a
This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding. [provided by RefSeq, Jul 2008]

Experiment Design Tools