NFkB p65 (pS536) / Unconjugated / REA348

Product Details

Description	Clone REA348 recognizes the human NF-kappaB p65 antigen phosphorylated at serine 529 (pS529). NF-kappaB is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis, and apoptosis. It is a homo- or heterodimeric complex and the heterodimeric p65-p50 complex is the most abundant one. Optimal induction of NF-kappaB target genes also requires phosphorylation of NF-kappaB proteins, such as p65, within their transactivation domain by a variety of kinases in response to distinct stimuli. \| Additional information: Clone REA348 displays negligible binding to Fc receptors.
Conjugate	Unconjugated
Clone	REA348
Target Species	Human
Applications	Mass Cytometry
Supplier	Miltenyi Biotec
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