About CCR7
The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]

About Spark YG 581
Spark YG™ 581 from Biolegend is a fluorophore designed for spectral flow cytometry with an excitation peak at 565 nm and an emission peak at 581 nm. This fluorophore is an alternative to Alexa Fluor™ 568 and efficiently excited by the 561 nm laser with minimal cross-beam excitation by the 488 nm laser.