PGC-1 alpha / DyLight 350 /

Product Details
Description PGC1 alpha Antibody [DyLight 350]
Conjugate DyLight 350
Clone
Target Species Goat, Hamster, Human, Mouse, Porcine, Rat, Squirrel
Applications FC, ICS, Knockout Validated, ICC, IF, IHC-P, WB, IHC-Fr, IHC
Supplier Novus Biologicals
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About PGC-1 alpha
The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. [provided by RefSeq, Jul 2008]
About DyLight 350
DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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