CD11c / APC-R700 / BU15

Product Details
Description APC-R700 Mouse Anti-Human CD11c
Conjugate APC-R700
Clone BU15
Target Species Human
Applications FC
Supplier BD Biosciences
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About CD11c
This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
About APC-R700
APC-R700 from BD Biosciences has an excitation peak at 651 nm and an emission peak at 705 nm. It's useful in flow cytometry and is spectrally similar to APC-Cy5.5, APC-Alexa 700, APC-Alexa 680 and Seta-APC-705.
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