SETD2 / Unconjugated /
Product Details
| Description | SETD2 (E4W8Q) Rabbit mAb (IHC Formulated) recognizes endogenous levels of total SETD2 protein. Staining of uncertain specificity in mouse granulocytes has been observed by immunohistochemistry. | |
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| Conjugate | Unconjugated | |
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| Target Species | Human, Monkey, Mouse | |
| Applications | FC, IF, IHC-P | |
| Supplier | Cell Signaling Technology | |
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About SETD2
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008]
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008]
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217 SETD2 antibodies from over 16 suppliers available with over 34 conjugates.
