CD27 / CF514 / 203.6
Product Details
Description | CD27 Monoclonal Mouse Antibody (203.6) | |
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Conjugate | CF514 | |
Clone | 203.6 | |
Target Species | Human | |
Applications | FC, IF | |
Supplier | Biotium | |
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About CD27
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]
About CF514
CF®514 from Biotium is a fluorophore with an excitation peak at 516 nm and an emission peak at 548 nm. It is spectrally similar to Alexa Fluor™ 514.
CF®514 from Biotium is a fluorophore with an excitation peak at 516 nm and an emission peak at 548 nm. It is spectrally similar to Alexa Fluor™ 514.
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