CD141 / CF405S / rTHBD/1591

Product Details
Description Thrombomodulin / CD141 Recombinant Monoclonal Mouse Antibody (rTHBD/1591)
Conjugate CF405S
Clone rTHBD/1591
Target Species Human
Applications ELISA, IHC-P
Supplier Biotium
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About CD141
The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [provided by RefSeq, Jul 2008]
About CF405S
CF®405S from Biotium is a fluorophore with an excitation peak at 404 nm and an emission peak at 431 nm. It is spectrally similar to Alexa Fluor™ 405. It can be use in fluorescence microscopy, specifically its been validated in Structured Illumination (SIM), and flow cytometry. However, in flow cytometry, superior alternatives are Brilliant™ Violet 421, SuperNova v428 and StarBright Violet 440.
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