About CD105
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]

About CF405L
CF®405L from Biotium is a fluorophore with an excitation peak at 395 nm and an emission peak at 545 nm. It is spectrally similar to Pacific Orange, Cascade Yellow and Krome Orange and can be used in flow cytometry. A superior alternative in flow cytometry is StarBright 570 and Brilliant™ Violet 510.