Catenin beta / Biotin / rCTNNB1/2173

Product Details
Description Catenin, Beta Recombinant Monoclonal Mouse Antibody (rCTNNB1/2173)
Conjugate Biotin
Clone rCTNNB1/2173
Target Species Human, Mouse, Rat
Applications IF, IHC-P
Supplier Biotium
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About Catenin beta
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]
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2144 Catenin beta antibodies from over 38 suppliers available with over 59 conjugates.

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