CCR6 / Brilliant Ultraviolet 737 / 11A9

Product Details
Description Hu CD196 (CCR6) BUV737 11A9 50Tst
Conjugate Brilliant Ultraviolet 737
Clone 11A9
Target Species Baboon, Cynomolgus, Human, Rhesus
Applications FC
Supplier BD Biosciences
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About CCR6
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
About Brilliant Ultraviolet 737
Brilliant™ UltraViolet 737 (BUV737) is a near infrared-emitting tandem fluorophore that combines BD Horizon® BUV395 and an acceptor dye. It can be excited by the 355 nm ultraViolet laser and collected using a 740/35 bandpass filter. BUV737 has an excitation peak at 498 nm and an emission peak at 732 nm BUV737 has a medium/high relative brightness, and is most commonly used for multicolor flow cytometry. This dye is part of the Brilliant™ UltraViolet dye family, developed and sold by BD Biosciences. This family of dyes uses BUV396 as the donor so that all dyes in the family can be excited by the 355 nm ultraViolet laser. Depending on the acceptor, the dyes in this family have different relative brightness ratings.
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