Aggrecan / DyLight 350 / B-C3

Product Details
Description Recognizes the aggrecanase (ADAMTS-1, -4 & -5)-generated N-terminal neoepitope ARG after cleavage between amino acids EGE and ARG within the interglobular domain of aggrecanase-catabolised aggrecan.
Conjugate DyLight 350
Clone B-C3
Target Species Bovine, Canine, Equine, Feline, Guinea Pig, Human, Mouse, Porcine, Rabbit, Rat, Sheep
Applications ELISA, ICC, IF, IHC-P, WB, IHC-Fr, IHC
Supplier Novus Biologicals
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About Aggrecan
This gene is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene. [provided by RefSeq, Jul 2008]
About DyLight 350
DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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426 Aggrecan antibodies from over 19 suppliers available with over 39 conjugates.

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