Catenin beta / DyLight 594 / 15B8

Product Details
Description Mouse beta-Catenin antibody [DyLight 594] detects Human, Mouse, Rat, Bovine, Canine, Chicken
Conjugate DyLight 594
Clone 15B8
Target Species Bovine, Canine, Chicken, Human, Mouse, Rat
Applications FC, ICC, IF, IHC-P, WB, IHC
Supplier Novus Biologicals
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About Catenin beta
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]
About DyLight 594
DyLight™ 594 has an excitation peak at 593 nm and an emission peak at 618 nm and is spectrally similar to Alexa Fluor™ 594 and Texas Red. DyLight™ 594 is most commonly used in flow cytometery and fluorescence microscopy applications.
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