GABA A Receptor alpha 4 / Alexa Fluor 700 / S398A-34

Product Details
Description Detects 60kDa. Does not cross-react with other GABA-A-Receptor Alpha subunits.
Conjugate Alexa Fluor 700
Clone S398A-34
Target Species Human, Mouse, Rat
Applications ICC, IF, WB, IHC
Supplier Novus Biologicals
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About GABA A Receptor alpha 4
Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1). Alternatively spliced transcript variants encoding different isoforms have been found in this gene.[provided by RefSeq, Feb 2011]
About Alexa Fluor 700
Alexa Fluor™ 700 (AF700, Alexa 700) has an excitation peak at 702 nm and an emission peak at 723 nm, and is spectrally similar to iFluor® 680 (ATT Bioquest) and iFluor® 700 (ATT Bioquest). Alexa 700 is commonly used in Flow Cytometry and is similar in size, brightness and application to iFluor® 700 and Vio® R720.
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58 GABA A Receptor alpha 4 antibodies from over 9 suppliers available with over 24 conjugates.

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