CD4 / PE-Texas Red / GK1.5

Product Details
Description Rat Anti-Mouse CD4-PE/TXRD - - -
Conjugate PE-Texas Red
Clone GK1.5
Target Species Mouse
Applications FC
Supplier SouthernBiotech
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About CD4
This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, May 2020]
About PE-Texas Red
PE-Texas Red is a red-emitting tandem fluorophore that combines pycoerythrin (PE) and Texas Ted. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Texas Red. PE-Texas Ted has an excitation peak at 565 nm and an emission peak at 615 nm. It is spectrally comparable to PE-eFluor™ 610, PE-Dazzle 594 and PE-CF®594.
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