MyD88 / DyLight 755 /

Product Details
Description Because of high sequence homology, this antibody is expected to detect multiple isoforms of MyD88 protein.
Conjugate DyLight 755
Clone
Target Species Chicken, Human, Mouse, Rat
Applications ICC, IF, IHC-P, WB, IHC
Supplier Novus Biologicals
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About MyD88
This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
About DyLight 755
DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy.
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