FK506 / Unconjugated / FK1
Product Details
| Description | NB100-62571 detects FK-506, a macrolide with similar but more potent immunosuppressant activity than cyclosporine. It is a 23-membered lactone produced by the bacteria Streptomyces tsukubaensis. FK-506 inhibits signal transduction and interleukin-2 transcription in CD4+ T helper lymphocytes, and is mainly used after allogenic organ transplantation to reduce organ rejection. Side effects of FK-506 treatment include nephrotoxicity, neurotoxicity, diabetes mellitus and hypertension. | |
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| Conjugate | Unconjugated | |
| Clone | FK1 | |
| Target Species | All Species | |
| Applications | ELISA | |
| Supplier | Novus Biologicals | |
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7 FK506 antibodies from over 5 suppliers available with over 1 conjugates.
