CD47 / Unconjugated / OX-101

Product Details

Description	Antibody recognizes the rat homologue of human CD47, which has been identified as the ligand for the rat signal regulatory protein (SIRP). Rat CD47 is expressed primarily by lymphocytes and macrophages but has also been detected at high levels on brain endothelial cells. Clone OX-101 has been reported to block the interaction of CD47 and SIRP.
Conjugate	Unconjugated
Clone	OX-101
Target Species	Rat
Applications	FC, WB, IP
Supplier	Novus Biologicals
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About CD47
This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2010]

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